Coleman of vigabatrin induced visual field defects
نویسندگان
چکیده
http://bjo.bmj.com/content/86/8/931.full.html Updated information and services can be found at: These include: References http://bjo.bmj.com/content/86/8/931.full.html#ref-list-1 This article cites 3 articles, 2 of which can be accessed free at: service Email alerting the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the box at Notes
منابع مشابه
Vigabatrin-induced peripheral visual field defects in patients with refractory partial epilepsy.
PURPOSE Vigabatrin can cause retinopathy, resulting in bilateral visual field constriction. Previous analyses of results from a prospective, observational study assessing vigabatrin-induced visual field constriction (described below) employed a partially subjective interpretation of static perimetery. To affirm these previous findings through more objective, quantitative methodology, we now rep...
متن کاملVisual field defects associated with vigabatrin therapy.
OBJECTIVE To estimate the prevalence of visual field defects in patients taking the anticonvulsant drug vigabatrin and to characterise the features of visual dysfunction found. METHODS Thirty three unselected patients attending neurology and epilepsy clinics were identified as taking vigabatrin and asked to attend for neuro-ophthalmic evaluation. A control group of 16 patients with epilepsy u...
متن کاملVisual defects associated with vigabatrin: a study of epileptic argentine patients.
OBJECTIVE The aim of the present study was to assess visual alterations in a population of Argentine patients treated with the antiepileptic drug vigabatrin. METHODS Twenty patients receiving vigabatrin and 15 patients receiving carbamazepine were examined with automated perimetry using a Humphrey 120-point full screening strategy. In addition, scotopic flash electroretinograms were performed...
متن کاملVigabatrin-Induced Retinal Toxicity Is Partially Mediated by Signaling in Rod and Cone Photoreceptors
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms that lead to these visual field defects are uncertain. Recent studies have demonstrated light exp...
متن کاملA controlled study of vigabatrin and visual abnormalities.
AIMS To assess the visual function in epileptic patients who have received vigabatrin; to compare this with the visual function in similar epileptic patients who have never received vigabatrin; to investigate whether the severity of visual field defect (VFD) is related to the dose of vigabatrin; to consider other factors that may correlate with the severity of VFD. METHODS 21 consecutive pati...
متن کامل